42 research outputs found
Constraining the relativistic mean-field model equations of state with gravitational wave observations
The first detection of gravitational waves from the binary neutron star
merger event GW170817 has started to provide important new constraints on the
nuclear equation of state at high density. The tidal deformability bound of
GW170817 combined with the observed two solar mass neutron star poses a serious
challenge to theoretical formulations of realistic equations of state. We
analyze a fully comprehensive set of relativistic nuclear mean-field theories
by confronting them with the observational bounds and the measured neutron-skin
thickness. We find that only a few models can withstand these bounds which
predict a stiff overall equation of state but with a soft neutron-proton
symmetry energy. Two possible indications are proposed: Circumstantial evidence
of hadron-quark phase transition inside the star and new parametrizations that
are consistent with ground state properties of finite nuclei and observational
bounds. Based on extensive analysis of these sets, an upper limit on the radius
of a neutron star of km is deduced.Comment: Matches with the published versio
On the Discovery of Success Trajectories of Authors
Understanding the qualitative patterns of research endeavor of scientific
authors in terms of publication count and their impact (citation) is important
in order to quantify success trajectories. Here, we examine the career profile
of authors in computer science and physics domains and discover at least six
different success trajectories in terms of normalized citation count in
longitudinal scale. Initial observations of individual trajectories lead us to
characterize the authors in each category. We further leverage this trajectory
information to build a two-stage stratification model to predict future success
of an author at the early stage of her career. Our model outperforms the
baseline with an average improvement of 15.68% for both the datasets.Comment: 2 pages, 1 figure in 25rd International World Wide Web Conference WWW
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A new over-dispersed count model
A new two-parameter discrete distribution, namely the PoiG distribution is
derived by the convolution of a Poisson variate and an independently
distributed geometric random variable. This distribution generalizes both the
Poisson and geometric distributions and can be used for modelling
over-dispersed as well as equi-dispersed count data. A number of important
statistical properties of the proposed count model, such as the probability
generating function, the moment generating function, the moments, the survival
function and the hazard rate function. Monotonic properties are studied, such
as the log concavity and the stochastic ordering are also investigated in
detail. Method of moment and the maximum likelihood estimators of the
parameters of the proposed model are presented. It is envisaged that the
proposed distribution may prove to be useful for the practitioners for
modelling over-dispersed count data compared to its closest competitors
A multiple k-means cluster ensemble framework for clustering citation trajectories
Citation maturity time varies for different articles. However, the impact of
all articles is measured in a fixed window. Clustering their citation
trajectories helps understand the knowledge diffusion process and reveals that
not all articles gain immediate success after publication. Moreover, clustering
trajectories is necessary for paper impact recommendation algorithms. It is a
challenging problem because citation time series exhibit significant
variability due to non linear and non stationary characteristics. Prior works
propose a set of arbitrary thresholds and a fixed rule based approach. All
methods are primarily parameter dependent. Consequently, it leads to
inconsistencies while defining similar trajectories and ambiguities regarding
their specific number. Most studies only capture extreme trajectories. Thus, a
generalised clustering framework is required. This paper proposes a feature
based multiple k means cluster ensemble framework. 1,95,783 and 41,732 well
cited articles from the Microsoft Academic Graph data are considered for
clustering short term (10 year) and long term (30 year) trajectories,
respectively. It has linear run time. Four distinct trajectories are obtained
Early Rise Rapid Decline (2.2%), Early Rise Slow Decline (45%), Delayed Rise No
Decline (53%), and Delayed Rise Slow Decline (0.8%). Individual trajectory
differences for two different spans are studied. Most papers exhibit Early Rise
Slow Decline and Delayed Rise No Decline patterns. The growth and decay times,
cumulative citation distribution, and peak characteristics of individual
trajectories are redefined empirically. A detailed comparative study reveals
our proposed methodology can detect all distinct trajectory classes.Comment: 29 page
Recent Results on Some Word Oriented Stream Ciphers: SNOW 1.0, SNOW 2.0 and SNOW 3G
In this chapter, we have studied three word-oriented stream ciphers SNOW 1.0, SNOW 2.0 and SNOW 3G in a detailed way. The detailed description includes the working principles of each cipher, security vulnerabilities and implementation issues. It also helps us to study the challenges in each cipher. As SNOW 3G is used as a confidentiality and integrity component in 3G, 4G and 5G communications, the after study of this article may instigate the reader to find the fixes from different cryptanalysis and also find a new suitable design in Mobile telephony security
Effect of Quaternary Ammonium Surfactant on Buccal Permeation of Budesonide Film Formulation: In Silico Docking Studies
Budesonide, an immunosuppressant glucocorticosteroid generally used to ameliorate chronic inflammation. Low bioavailability due to first pass metabolism decreases its therapeutic activity. The present study focuses on the formulation of a biodegradable buccoadhesive film for improvement of buccalpermeation. Transparent buccoadhesive films were prepared by incorporating budesonide in HPMC matrix with triethalonamine as a plasticizer and a number of surfactants. Absence of the characteristic drug melting peak at 252°C in Differential Scanning Calorimetry (DSC) thermogram study confirmed almost complete amorphization of the drug to a homogenous solid-solid mixture in the film. The characteristic Fourier-Transform Infrared Spectroscopy (FTIR) peak of pure drug showed the carbonyl stretching in between 1600–1900 cm−1 and C–O stretching at 1095 cm−1. Broadening of C–O stretching and masking of carbonyl stretching confirmed the drug polymer interaction. In vitro dissolution and ex-vivo buccal tissue permeation revealed upto 72% and more than 58% respectively using surfactants upto 6 hour of study. Enhanced buccal permeability and flux were found in presence of surfactant compared to its absence. New film formulation could be developed including surfactant for improved buccal permeation with expected increased bioavailability. The in silico study confirmed about a stable interaction between drug and polymer (−3.1 kcal/mol)
Hydrogen Bond Dynamics Near A Micellar Surface: Origin of the Universal Slow Relaxation at Complex Aqueous Interfaces
The dynamics of hydrogen bonds among water molecules themselves and with the
polar head groups (PHG) at a micellar surface have been investigated by long
molecular dynamics simulations. The lifetime of the hydrogen bond between a PHG
and a water molecule is found to be much longer than that between any two water
molecules, and is likely to be a general feature of hydrophilic surfaces of
organized assemblies. Analyses of individual water trajectories suggest that
water molecules can remain bound to the micellar surface for more than a
hundred picosecond. The activation energy for such a transition from the bound
to a free state for the water molecules is estimated to be about 3.5kcal/mole.Comment: 12 pages. Phys. Rev. Lett. (Accepted) (2002